alpha-aMine-oMega-propionic acid diethylene glycol
α-amine-ω-propionic acid diethylene glycol
CAS: 791028-27-8
Molecular Formula: C7H15NO4
alpha-aMine-oMega-propionic acid diethylene glycol - Names and Identifiers
alpha-aMine-oMega-propionic acid diethylene glycol - Physico-chemical Properties
| Molecular Formula | C7H15NO4 |
| Molar Mass | 177.2 |
| Density | 1.142±0.06 g/cm3(Predicted) |
| Boling Point | 331.5±27.0 °C(Predicted) |
| pKa | 4.27±0.10(Predicted) |
| Storage Condition | Keep in dark place,Inert atmosphere,Room temperature |
| Use | Amino-PEG2-C2-acid is a degradable (cleavable) 3-unit PEG ADC linker used in the synthesis of antibody-coupled drugs (ADC). Amino-PEG2-C2-acid is also a PEG-based PROTAC linker, which can be used for PROTAC synthesis. |
alpha-aMine-oMega-propionic acid diethylene glycol - Preparation solution concentration reference
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 5.643 ml | 28.217 ml | 56.433 ml |
| 5 mM | 1.129 ml | 5.643 ml | 11.287 ml |
| 10 mM | 0.564 ml | 2.822 ml | 5.643 ml |
| 5 mM | 0.113 ml | 0.564 ml | 1.129 ml |
Last Update：2024-01-02 23:10:35
alpha-aMine-oMega-propionic acid diethylene glycol - Introduction
Target
Cleavable
PEGs
In vitro study
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
Last Update：2024-04-09 19:04:56
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CAS: 791028-27-8
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CAS: 791028-27-8
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
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